The Definitive Guide to traditional medicine
Also, Hsu et al. [62] postulated the mATXN3 protein undergoes proteolytic cleavage to the removing on the N-terminus, leading to the progression of SCA3. Proteolytic cleavage with the mATXN3 protein is observed to produce poisonous fragments often known as truncated C-terminal fragments, which appear as intranuclear aggregates while in the brain sa